Variable

Number

Disease-free survival

Overall survival

RR (95% CI)

P value

RR (95% CI)

P value

Gender

Male

77

1.7 (0.8 - 3.7)

0.18

1.3 (1.1 - 4.8)

0.03

Female

47

Tumor size

< 5 cm

50

≥ 5 cm

74

2.2 (1.0 - 4.9)

0.05

1.7 (0.8 - 3.3)

0.15

Age

<65 yrs

48

≥65 yrs

76

1.5 (0.7 - 3.2)

0.30

2.0 (1.0 - 4.0)

0.07

T stage

T2

65

T3

59

5.0 (2.1 - 12).4)

＜0.01

2.3 (1.2 - 4.4)

0.02

N stage

Negative

104

Positive

20

5.6 (2.7 - 11.5)

＜0.01

3.4 (1.3 - 8.7)

0.01

Lymph vessel invasion

Negative

32

Positive

90

3.4 (1.0 - 11.2)

0.01

1.5 (0.7 - 3.5)

0.32

Unknown

2

Blood vessel invasion

Negative

36

Positive

84

2.4 (0.9 - 6.3)

0.07

1.8 (0.8 - 3.9)

0.15

Unknown

4

Histological grade

Well differentiated

27

Others

97

1.0 (0.4 - 2.5)

0.93

0.5 (0.3 - 1.0)

0.06

Intraoperative blood loss

Low

93

High

31

3.0 (1.2 - 7.9)

0.03

2.1 (0.9 - 4.7)

<0.01

Ezrin expression

Negative group

87

4.5 (1.4 - 14.7)

0.01

2.1 (0.9 - 4.7)

0.08

Positive group

37