Compound

Cancer

Cell lines

In vitro anticancer activities of benzimidazolyl-retrochalcones (IC₅₀ at µM)

Hepatitis

Prostate

Non-small cell lung

Colon

Breast

Fibroblast

Huh-7

PC3

NCI-H727 [24]

CaCo2

HCT-116

MDA-MB 231

MCF-7

1

7.77

4.17

2.83

5.25

1.48

3.92

5.02

4.60

2

2.17

1.08

1.54

1.32

0.83

1.13

1.56

0.91

3

4.02

3.01

3.15

2.64

2.73

2.58

3.22

2.00

4

2.91

1.83

2.20

2.16

2.39

1.35

2.57

0.61

5

11.26

9.57

8.63

10.73

8.01

12.60

7.71

5.88

6

4.35

2.32

1.98

3.58

0.86

1.61

2.80

2.91

7

2.05

2.59

2.50

2.69

1.92

1.42

4.70

3.15

8

7.64

2.67

2.71

4.06

4.99

2.80

2.50

7.54

9

8.83

4.03

4.89

4.16

7.48

7.44

2.91

4.71

10

4.54

3.13

2.82

3.32

3.92

2.26

3.60

3.23

11

6.77

1.78

3.59

4.09

4.76

4.32

3.57

8.02

12

8.46

3.89

4.61

5.52

3.66

6.56

5.45

5.95

13

5.17

14.70

6.35

9.88

8.86

9.73

4.52

9.29

Roscovitine

16

11

16

17

8

18

11

3

Paclitaxel

0.01

0.001

0.002

0.03

0.004

0.04

0.01

>0.25