Compound

Molecular weight

IC50 (μM)

MDA-231

SGC-7901

5a

288.11

66.23 ± 0.96

184.54 ± 1.24

5b

288.11

51.27 ± 0.84

---

5c

340.17

50.19 ± 1.02

122.68 ± 2.04

10a

316.14

440.22 ± 0.78

284.5 ± 2.36

10b

344.17

57.08 ± 0.32

---

10c

272.12

64.06 ± 0.27

---

5-FU

262.19

98.59 ± 0.74

156.74 ± 2.64

Resveatrol

228.24

153.32 ± 0.64

184.3 ± 1.38