structures | R1 | R2 | Predicted pIC50 |
D1 | R11 | 2-CH2CH3 | 5.710 |
D2 | R11 | 3-CH2CH3 | 5.541 |
D3 | R11 | 4-CH2CH3 | 5.094 |
D4 | R11 | 2-Cl,3-CH3 | 5.966 |
D5 | R11 | 2-CH3,3-Cl | 5.896 |
D6 | R11 | 2- Br,3-CH3 | 5.921 |
D7 | R11 | 2-CH3,3-Br | 5.895 |
N1 | R12 | 2-CH2CH3 | 6.090 |
N2 | R12 | 3-CH2CH3 | 6.101 |
N3 | R12 | 4-CH2CH3 | 5.621 |
N4 | R12 | 2-Cl,3-CH3 | 6.050 |
N5 | R12 | 2-CH3,3-Cl | 5.620 |
N6 | R12 | 2-Br,3-CH3 | 6.064 |
N7 | R12 | 2-CH3,3-Br | 5.609 |