structures

R₁

R₂

Predicted pIC₅₀

D1

R₁₁

2-CH₂CH₃

5.710

D2

R₁₁

3-CH₂CH₃

5.541

D3

R₁₁

4-CH₂CH₃

5.094

D4

R₁₁

2-Cl,3-CH₃

5.966

D5

R₁₁

2-CH₃,3-Cl

5.896

D6

R₁₁

2- Br,3-CH₃

5.921

D7

R₁₁

2-CH₃,3-Br

5.895

N1

R₁₂

2-CH₂CH₃

6.090

N2

R₁₂

3-CH₂CH₃

6.101

N3

R₁₂

4-CH₂CH₃

5.621

N4

R₁₂

2-Cl,3-CH₃

6.050

N5

R₁₂

2-CH₃,3-Cl

5.620

N6

R₁₂

2-Br,3-CH₃

6.064

N7

R₁₂

2-CH₃,3-Br

5.609