structures

R1

R2

Predicted pIC50

D1

R11

2-CH2CH3

5.710

D2

R11

3-CH2CH3

5.541

D3

R11

4-CH2CH3

5.094

D4

R11

2-Cl,3-CH3

5.966

D5

R11

2-CH3,3-Cl

5.896

D6

R11

2- Br,3-CH3

5.921

D7

R11

2-CH3,3-Br

5.895

N1

R12

2-CH2CH3

6.090

N2

R12

3-CH2CH3

6.101

N3

R12

4-CH2CH3

5.621

N4

R12

2-Cl,3-CH3

6.050

N5

R12

2-CH3,3-Cl

5.620

N6

R12

2-Br,3-CH3

6.064

N7

R12

2-CH3,3-Br

5.609