I. BL

II. 3 M

III. 6 M

IV. 9 M

V. 12 M

VI. 15 M

VII. 18 M

ANOVA

Group A (n = 24)

6.3 ± 2.6

6.3 ± 2.8

6.3 ± 2.4

7.0 ± 2.6

7.7 ± 2.6

7.8 ± 2.7

7.9 ± 2.4

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Placebo A (n = 22)

7.3 ± 2.8

5.5 ± 3.5

5.8 ± 2.7

6.7 ± 2.7

7.0 ± 3.0

6.3 ± 2.0

6.1 ± 2.8

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Group B (n = 32)

11.8 ± 1.6

12.0 ± 1.4

11.9 ± 1.5

11.8 ± 1.3

11.8 ± 1.6

12.0 ± 1.4

12.0 ± 1.3

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Placebo B (n = 20)

7.5 ± 2.8

7.2 ± 3.1

6.3 ± 2.6

6.9 ± 2.6

7.3 ± 3.0

6.5 ± 2.7

6.3 ± 2.7

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