| I. BL | II. 3 M | III. 6 M | IV. 9 M | V. 12 M | VI. 15 M | VII. 18 M | ANOVA |
Group A (n = 24) | 6.3 ± 2.6 | 6.3 ± 2.8 | 6.3 ± 2.4 | 7.0 ± 2.6 | 7.7 ± 2.6 | 7.8 ± 2.7 | 7.9 ± 2.4 | _ |
Placebo A (n = 22) | 7.3 ± 2.8 | 5.5 ± 3.5 | 5.8 ± 2.7 | 6.7 ± 2.7 | 7.0 ± 3.0 | 6.3 ± 2.0 | 6.1 ± 2.8 | _ |
Group B (n = 32) | 11.8 ± 1.6 | 12.0 ± 1.4 | 11.9 ± 1.5 | 11.8 ± 1.3 | 11.8 ± 1.6 | 12.0 ± 1.4 | 12.0 ± 1.3 | _ |
Placebo B (n = 20) | 7.5 ± 2.8 | 7.2 ± 3.1 | 6.3 ± 2.6 | 6.9 ± 2.6 | 7.3 ± 3.0 | 6.5 ± 2.7 | 6.3 ± 2.7 | _ |