| I. BL | II. 3 M | III. 6 M | IV. 9 M | V. 12 M | VI. 15 M | VII. 18 M | ANOVA |
Group A (n = 24) | 19.9 ± 2.5 | 20.2 ± 2.8 | 21.0 ± 3.5 | 21.7 ± 3.2 | 21.9 ± 3.0 | 22.1 ± 3.5 | 22.9 ± 3.2 | I < V* I < VI* I < VII* |
Placebo A (n = 22) | 18.2 ± 4.3 | 17.2 ± 4.5 | 17.7 ± 4.7 | 17.5 ± 4.8 | 17.2 ± 5.4 | 16.0 ± 5.3 | 16.0 ± 5.0 | _ |
Group B (n = 32) | 19.9 ± 5.9 | 21.3 ± 4.9 | 21.3 ± 4.7 | 21.1 ± 5.2 | 21.7 ± 4.5 | 22.2 ± 4.8 | 22.3 ± 5.0 | _ |
Placebo B (n = 20) | 18.7 ± 4.3 | 17.6 ± 4.7 | 18.0 ± 4.8 | 18.0 ± 4.8 | 17.4 ± 4.3 | 16.5 ± 4.9 | 15.4 ± 4.2 | I > VII* |