| B | SE | t value | p | |
| PRO-INFLAMMATORY | ||||
| Log CRP (mg/L) | ||||
| Intent-to-treat (ITT) analysis |
| |||
| Time | 0.07 | 0.04 | 1.82 | 0.071 |
| Main effect of group | 0.10 | 0.13 | 0.77 | 0.441 |
| Group × time interaction | −0.07 | 0.06 | −1.17 | 0.242 |
| Per-protocol (PP) analysis | ||||
| Time | 0.09 | 0.04 | 2.03 | 0.044 |
| Main effect of group | 0.13 | 0.15 | 0.87 | 0.385 |
| Group × time interaction | −0.09 | 0.06 | −1.51 | 0.135 |
| Log TNF-α (pg/ml) | ||||
| Intent-to-treat analysis | ||||
| Time | −0.01 | 0.01 | −1.40 | 0.163 |
| Main effect of group | 0.01 | 0.04 | 0.30 | 0.767 |
| Group × time interaction | 0.00 | 0.01 | −0.02 | 0.98 |
| Per-protocol analysis | ||||
| Time | 0.00 | 0.01 | −0.41 | 0.681 |
| Main effect of group | 0.05 | 0.04 | 1.18 | 0.242 |
| Group × time interaction | −0.01 | 0.01 | 0.60 | 0.549 |
| Log IL-1β (pg/ml) | ||||
| Intent-to-treat analysis | ||||
| Time | −0.03 | 0.03 | −1.06 | 0.293 |
| Main effect of group | 0.04 | 0.14 | 0.30 | 0.765 |
| Group × time interaction | 0.04 | 0.04 | 0.81 | 0.417 |
| Per-protocol analysis | ||||
| Time | −0.03 | 0.03 | −0.77 | 0.442 |
| Main effect of group | 0.03 | 0.17 | 0.16 | 0.874 |
| Group × time interaction | 0.03 | 0.05 | 0.69 | 0.492 |
| Log IFN-γ (pg/ml) | ||||
| Intent-to-treat analysis | ||||
| Time | −0.02 | 0.02 | −1.19 | 0.237 |
| Main effect of group | 0.05 | 0.10 | 0.45 | 0.654 |
| Group × time interaction | 0.02 | 0.03 | 0.81 | 0.417 |
| Per-protocol analysis | ||||
| Time | −0.02 | 0.02 | −0.67 | 0.501 |
| Main effect of group | 0.02 | 0.13 | 0.16 | 0.876 |
| Group × time interaction | 0.02 | 0.03 | 0.71 | 0.478 |