| Measures | Treatment | TRT × Day, P-value | |
| Control | Probiotic | ||
| Plasma Cortisol, ng/mL |
|
| 0.042 |
| Day 7 | 32.8 ± 6.68 | 38.5 ± 6.30 |
|
| Day 14 | 31.2 ± 6.26a | 51.0 ± 6.26b |
|
| Day 21 | 45.0 ± 5.99 | 36.9 ± 5.99 |
|
| Day 28 | 45.6 ± 5.99 | 47.7 ± 6.30 |
|
| White Blood Cell (WBC), 107/10 μL |
|
| 0.643 |
| Day 7 | 1.56 ± 0.30 | 1.75 ± 0.30 |
|
| Day 14 | 1.36 ± 0.31 | 1.93 ± 0.31 |
|
| Day 21 | 1.38 ± 0.30 | 1.79 ± 0.30 |
|
| Day 28 | 1.66 ± 0.30 | 1.74 ± 0.31 |
|
| Neutrophils, % |
|
| 0.179 |
| Day 7 | 37.7 ± 4.87 | 53.3 ± 4.87 |
|
| Day 14 | 41.5 ± 5.03 | 47.3 ± 5.03 |
|
| Day 21 | 43.1 ± 4.87 | 48.1 ± 4.87 |
|
| Day 28 | 51.2 ± 4.87 | 50.6 ± 5.04 |
|
| Lymphocytes, % |
|
| 0.747 |
| Day 7 | 50.5 ± 4.11 | 43.3 ± 4.11 |
|
| Day 14 | 56.3 ± 4.31 | 47.9 ± 4.31 |
|
| Day 21 | 52.3 ± 4.11 | 45.7 ± 4.11 |
|
| Day 28 | 45.8 ± 4.11 | 45.2 ± 4.31 |
|
| Monocytes, % |
|
| 0.328 |
| Day 7 | 9.18 ± 2.71 | 2.18 ± 2.71 |
|
| Day 14 | 0.77 ± 2.84 | 1.72 ± 2.84 |
|
| Day 21 | 3.18 ± 2.71 | 3.62 ± 2.71 |
|
| Day 28 | 3.18 ± 2.71 | 3.36 ± 2.84 |
|
| Eosinophils, % |
|
| 0.918 |
| Day 7 | 5.22 ± 1.59 | 5.56 ± 1.59 |
|
| Day 14 | 5.24 ± 1.65 | 7.17 ± 1.65 |
|
| Day 21 | 5.44 ± 1.59 | 6.56 ± 1.59 |
|
| Day 28 | 3.89 ± 1.59 | 5.15 ± 1.66 |
|
| Neutrophil-to-Lymphocyte ratio |
|
| 0.068 |
| Day 7 | 0.82 ± 0.20x | 1.58 ± 0.20y |
|
| Day 14 | 0.93 ± 0.21 | 1.08 ± 0.21 |
|
| Day 21 | 0.97 ± 0.20 | 1.14 ± 0.20 |
|
| Day 28 | 1.24 ± 0.20 | 1.21 ± 0.21 |
|
| Chemotaxis-C5a, no./5 fields |
|
| 0.960 |
| Day 7 | 99.1 ± 21.9 | 136.0 ± 22.2 |
|
| Day 14 | 73.5 ± 22.8 | 124.2 ± 22.7 |
|
| Day 21 | 116.9 ± 23.8 | 155.2 ± 25.2 |
|
| Day 28 | 121.2 ± 21.4 | 153.4 ± 23.0 |
|
| Chemotaxis-IL8, no./5 fields |
|
| 0.452 |
| Day 7 | 85.1 ± 27.5 | 179.8 ± 27.1 |
|
| Day 14 | 63.1 ± 29.1 | 95.2 ± 30.0 |
|
| Day 21 | 85.9 ± 30.8 | 133.9 ± 26.4 |
|
| Day 28 | 89.2 ± 26.3 | 133.7 ± 26.8 |
|
| Neutrophil phagocytosis, % |
|
| 0.042 |
| Day 7 | 31.9 ± 5.78 | 38.66 ± 6.06 |
|
| Day 14 | 55.8 ± 5.93 | 51.85 ± 6.11 |
|
| Day 21 | 53.9 ± 5.78 | 49.32 ± 5.78 |
|
| Day 28 | 44.6 ± 5.85a | 59.80 ± 6.28b |
|
| Natural killer cell cytotoxicity, % |
|
| 0.080 |
| Day 7 | 27.6 ± 11.3 | 18.0 ± 11.3 |
|
| Day 14 | 36.5 ± 11.0 | 21.9 ± 11.1 |
|
| Day 21 | 22.9 ± 9.22 | 34.9 ± 9.88 |
|
| Day 28 | 23.5 ± 10.8x | 54.5 ± 10.9y |
|
| Concanavalin-A proliferation, index |
|
| 0.937 |
| Day 7 | 1.13 ± 0.35 | 1.17 ± 0.35 |
|
| Day 14 | 0.71 ± 0.36 | 0.62 ± 0.36 |
|
| Day 21 | 1.14 ± 0.35 | 0.93 ± 0.35 |
|
| Day 28 | 0.88 ± 0.37 | 1.04 ± 0.43 |
|
| Lipopolysaccharide proliferation, index |
|
| 0.467 |
| Day 7 | 1.51 ± 0.41 | 2.51 ± 0.41 |
|
| Day 14 | 0.96 ± 0.44 | 1.59 ± 0.44 |
|
| Day 21 | 2.10 ± 0.41 | 1.81 ± 0.41 |
|
| Day 28 | 1.31 ± 0.51 | 1.64 ± 0.72 |
|
| Interleukin-12, pg/mL |
|
| 0.265 |
| Day 7 | 160.2 ± 26.5 | 183.6 ± 26.5 |
|
| Day 14 | 139.8 ± 27.6 | 201.8 ± 27.7 |
|
| Day 21 | 199.0 ± 26.5 | 180.4 ± 26.6 |
|
| Day 28 | 180.4 ± 26.5 | 163.8 ± 27.8 |
|