| extended-release Naltrexone (Vivitrol 380 mg) (n = 1500) | long-acting Nalmefene (Nalmefene Consta 393.1 mg) (n = 1500) |
Alanine aminotransferase increased | 150 (10%) | 90 (6%) |
Aspartate aminotransferase increased | 90 (6%) | 30 (2%) |
Gamma-glutamyltransferase increased | 60 (4%) | 45 (3%) |
Nasopharyngitis | 120 (8%) | 60 (4%) |
Insomnia | 120 (8%) | 45 (3%) |
Influenza | 75 (5%) | 60 (4%) |
Hypertension | 60 (4%) | 45 (3%) |
Injection site pain | 120 (8%) | 30 (2%) |
Toothache | 60 (4%) | 30 (2%) |
Headache | 45 (3%) | 30 (2%) |