long-acting Nalmefene

(Nalmefene Consta 393.1 mg) (n = 1500)

extended-release Naltrexone (Vivitrol 380 mg)

(n = 1500)

Age in years

27.1 (±4.8)

28.3 (±3.6)

Sex

No. (%)

No. (%)

Male

1110 (74%)

1080 (72%)

Female

390 (26%)

420 (28%)

Marital status

No. (%)

No. (%)

Never married

765 (51%)

780 (52%)

Married/de facto

585 (39%)

570 (38%)

Divorced/separated

150 (10%)

150 (10%)

Race

No. (%)

No. (%)

White

663 (44.2%)

691 (46.1%)

Asian

256 (17.1%)

335 (22.3%)

Black

489 (32.6%)

445 (29.7%)

Others

92 (6.1%)

29 (1.9%)

Employment status

No. (%)

No. (%)

Student

210 (14%)

285 (19%)

Employed (full/part time)

795 (53%)

750 (50%)

Unemployed/pension

495 (33%)

465 (31%)

Duration of opioid dependence in years

9.1 (±4.5)

10.0 (±3.9)

Distribution of Duration of Opiate Dependence

No. (%)

No. (%)

<5 years

300 (20%)

255 (17%)

5 - 9 years

360 (24%)

315 (21%)

10 - 14 years

675 (45%)

630 (42%)

>15 years

165 (11%)

300 (20%)

Opioid craving scale

18 (±2)

22 (±2)

Hepatitis C positive

1170 (78%)

1275 (85%)

Opiate used in 30 days prior to baseline assessment

No. (%)

No. (%)

Heroin

1170 (78%)

1155 (77%)

Methadone

135 (9%)

195 (13%)

Other opiates/analgesics

195 (13%)

150 (10%)

Injecting (intravenous) users

930 (62%)

915 (61%)