| N˚ | Title | Journal | Authors | Country | Type of study | Type of intervention | Type of road users | Outputs | Implementation period | Risk of bias |
| 1 | An econometric study of the road safety impact of Nigeria’s federal road safety commission | International Journal of Soft Computing 2 (2): 279-284 | K. U. Nnadi et C. C. Ibe | Nigeria | Interrupted time series | Institutional strengthening | All types of users | Reduction in road traffic fatalities, injuries, crash cases | Intervention lasting three months or more | High |
| 2 | Modelling the impact of intervention measures on total accident cases in Nigeria using Box-Jenkins methodology: A case study of federal road safety commission | Cogent Engineering 2017; 4: 1345043 | B. U. Oreko, C. C. Nwobi-Okoye, S. Okiy & A. C. Igboanugo | Nigeria | Interrupted time series | Institutional strengthening | All types of users | Reduction in road traffic fatalities, crash cases, severity | Intervention lasting three months or more | Moderate |
| 3 | The crash helmet legislation in Nigeria: A before-and-after study | Acrid Anal. & Pm 1980; 12: 213-216 | S. E. Asogwa | Nigeria | quasi experimental no-randomized | Law enforcement | Drivers or passengers of two- or three- wheeled vehicles | Reduction in road traffic fatalities, Helmet use | Intervention lasting three months or more | High |
| 4 | The Role of Seat Belt in the Prevention of Fatalities and Determination of Fatality Index of Road Traffic Accidents in Rivers State, Nigeria | The Nigerian Health Journal 2013; 13 (4) | B. O. Akinbami | Nigeria | quasi experimental no-randomized | Law enforcement | Drivers or passengers of vehicles with more than three wheels | Reduction in road traffic fatalities, in injuries | Intervention lasting three months or more | High |
| 5 | Influence of road speed restrictions on the incidence and severity of head injuries | S Afr Med J 1973; 47 (12) | A. P. Rose-Innes & C. G. J. Le Roux | South Africa | quasi experimental no-randomized | Law enforcement | All motorised vehicle users | Reduction in injuries and severity | Intervention lasting three months or more | High |
| 6 | The Relationship between Speed Restrictions and Head Injury Admissions to Groote Schuur Hospital | S Afr Med J. 1974 Dec 14; 48 (61): 2546-8 | R. A. De Villiers & J. C. De Villiers | South Africa | quasi experimental no-randomized | Law enforcement | All motorised vehicle users | Reduction in road traffic fatalities, emergency room admissions for trauma, hospital stays | Intervention lasting three months or more | High |
| 7 | The impact of alcohol and road traffic policies on crash rates in Botswana, 2004-2011: a time-series analysis | Accid Anal Prev. 2014 September; 70: 33-39. | M. Sebego, et al. | Botswana | Interrupted time series | Law enforcement | All types of users | Reduction in road traffic fatalities, in crash cases | Intervention lasting three months or more | Moderate |
| 8 | Pattern of injuries from motorcycle accidents in Abia State, Nigeria: The influence of government regulation | Journal of Medical Investigations and Practice 2014; 9 (1) | O. E. Ugochukwu Ikeanyi, I. C. Nnezianya, H. I. Nwokeukwu & D. U. Inya-Agha | Nigeria | quasi experimental no-randomized | Law enforcement | Drivers or passengers of two- or three- wheeled vehicles | Reduction in road traffic fatalities, in emergency room admissions for trauma, in the severity | Intervention lasting three months or more | High |
| 9 | Impact of transportation policy on injury characteristics in a teaching hospital, Calabar, Nigeria | Int J Burn Trauma 2013; 3 (4): 214-219 | I. A. Ikpeme et al. | Nigeria | Interrupted time series | Law enforcement | Drivers or passengers of two- or three- wheeled vehicles | Reduction in road traffic fatalities, in emergency room admissions for trauma, in the severity | Intervention lasting three months or more | High |
| 10 | Helmet wearing in Kenya: prevalence, knowledge, attitude, practice and implications | Public health 144 (2017) S23-S31 | A. M. Bachani et al. | Kenya | quasi experimental no-randomized | Law enforcement | Drivers or passengers of two-or three- wheeled vehicles | Prevalence of helmet use before and after this legislation: KAP surrounding helmet use, and road traffic crashes and injuries among motorcyclists | Intervention repeated more than once | Moderate |
| 11 | A comparative evaluation of the impact of average speed enforcement (ASE) on passenger and minibus taxi vehicle drivers on the R61 in South Africa | J S Afr Inst Civ Eng 2016; 58 (4): 2-10 | N. A. Ebot Eno Akpa, M. J. Booysen, M. Sinclair | South Africa | quasi experimental no-randomized | Law enforcement | Drivers or passengers of vehicles with more than three wheels | Reduction in travel speeds during enforcement; Reduction in crash, fatality and serious injury rates; Level of driver understanding of ASE system | Intervention lasting three months or more | Moderate |
| 12 | An interactive computer program for South African urban primary school children to learn about traffic signs and rules | African Safety Promotion Journal 2018; 16 (1) | A. Fransman, B. Richter & S. Raath | South Africa | quasi experimental no-randomized | Awareness raising, training or user education interventions | Pedestrians | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | Moderate |
| 13 | Building capacity of drivers in Nigeria to provide first aid for road crash victims | Injury Prevention 2012; 18: 62-65 | A. O. Sangowawa & E. T. Owoaje | Nigeria | quasi experimental randomized | Awareness raising, training or user education interventions | Drivers or passengers of vehicles with more than three wheels | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | Low |
| 14 | Effect of First Aid Education on First Aid Knowledge and Skills of Commercial Drivers in South West Nigeria | Prehosp Disaster Med 2015 Dec; 30 (6): 579-85 | A. O. Olumide, M. Asuzu & O. O. Kale | Nigeria | quasi experimental randomized | Awareness raising, training or user education interventions | Drivers or passengers of vehicles with more than three wheels | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | Low |
| 15 | Effect of health education on the riding habits of commercial motorcyclists in Uyo, southern Nigeria | West African journal of medicine Nov 2012; 31 (1): 39-46 | O. E. Johnson et E. T. Owoaje | Nigeria | quasi experimental no-randomized | Awareness raising, training or user education interventions | Drivers or passengers of two- or three-wheeled vehicles | Reduction in crash cases, Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | High |
| 16 | Effect of safety education on knowledge of and compliance with road safety signs among commercial motorcyclists in Uyo, Southern Nigeria | Ghana Med J. 2011 Sep; 45 (3): 89-96 | O. E. Johnson et A. M. Adebayo | Nigeria | quasi experimental no-randomized | Awareness raising, training or user education interventions | Drivers or passengers of two- or three-wheeled vehicles | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | High |
| 17 | Effectiveness of road safety education in Nigeria using a quasi-experimental trial: Findings from the Road Safety Intervention Project | African Safety Promotion 2014; 12: 1-17. | I. P. Okafor et al. | Nigeria | quasi experimental randomized | Awareness raising, training or user education interventions | Drivers or passengers of vehicles with more than three wheels | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | Intervention repeated more than once | Moderate |
| 18 | Heckle and Chide: Results of a randomized road safety intervention in Kenya | Journal of Public Economics 2011; 95: 1438-1446 | J. Habyarimana & W. Jack | Kenya | quasi experimental randomized | Awareness raising, training or user education interventions | Drivers or passengers of vehicles with more than three wheels | Others: insurance claims data | Intervention lasting three months or more | Moderate |
| 19 | Results of a large-scale randomized behaviour change intervention on road safety in Kenya | PNAS August 25, 2015 112 (34) E4661-E4670 | J. Habyarimana & W. Jack | Kenya | quasi experimental randomized | Awareness raising, training or user education interventions | Drivers or passengers of vehicles with more than three wheels | Reduction in crash cases, Reduction in speeding, Others: insurance claims data | Intervention lasting three months or more | Low |
| 20 | Estimating effects of Uber ride-sharing service on road traffic-related deaths in South Africa: A quasi- experimental study | J Epidemiol Community Health 2019; 73: 263 | J. Y Huang, F. Majid & M. Daku | South Africa | Interrupted time series | Development of an Uber transport service | All types of users | Reduction in road traffic fatalities | Intervention lasting three months or more | Moderate |
| 21 | Effect of free distribution of safety equipment on usage among motorcycle-taxi drivers in Tanzania: A cluster randomised controlled trial | Injury. 2014 November; 45 (11): 1681-1686. | S. A. Sumner et al. | Tanzania | quasi experimental randomized | Distribution of helmets and reflective vests | Drivers or passengers of two- or three-wheeled vehicles | Improved knowledge and behaviour regarding traffic rules, laws and protective measures | One-off intervention (less than a week) | Low |
| 22 | Effectiveness of an improved road safety policy in Ethiopia: an interrupted time series study | BMC Public Health 2014; 14: 539 | T. Abegaz, Y. Berhane, A. Worku & A. Assrat | Ethiopia | Interrupted time series | Multi- intervention | All types of users | Reduction in road traffic fatalities, in injuries, in crash cases | Intervention lasting three months or more | Moderate |
| 23 | Effects of enforcement of the traffic act on injury severity among patients admitted at the Rift Valley Provincial General Hospital, Nakuru | East Afr Med J. 2010 Nov; 87 (11): 436-442 | E. Muguku, J. Ouma & A. Yitambe | Kenya | quasi experimental no-randomized | Multi- intervention | Drivers or passengers of vehicles with more than three wheels | Reduction in road traffic fatalities, in the severity, in hospital stays | Intervention lasting three months or more | High |
| 24 | Lives saved by laws and regulations that resulted from the Bloomberg road safety program | Accident Analysis and Prevention 2018; 113: 131-136 | T. R. Miller, D. T. Levy & D. I. Swedler | Brazil China Kenya Mexico Turkey Vietnam | quasi experimental no-randomized | Multi-intervention | All types of users | Reduction in road traffic fatalities | Intervention lasting three months or more | Moderate |
| 25 | Motorcycle taxi programme increases safe riding behaviours among its drivers in Kampala, Uganda | Inj Prev 2018; 0: 1-6. | K. Muni et al | Uganda | Cross- selectional | Multi- intervention | Drivers or passengers of two- or three- wheeled vehicles | Reduction in crash cases, Improved knowledge and behaviour regarding traffic rules, laws and protective measures | Intervention lasting three months or more | High |
| 26 | School Area Road Safety Assessment and Improvements (SARSAI) programme reduces road traffic injuries among children in Tanzania | Inj Prev 2019; 25: 414-420 | A. Poswayo, et al. | Tanzania | quasi experimental no-randomized | Multi- intervention | Pedestrians | Reduction in injuries, Reduction in crash cases | Intervention lasting three months or more | Moderate |
| 27 | Schoolbus driver performance can be improved with driver training, safety incentivisation, and vehicle roadworthy modifications | S Afr Med J 2017; 107 (3): 188-191 | A. van Niekerk, R. Govender, R. Jacobs, A. B. van As | South Africa | quasi experimental no-randomized | Multi- intervention | Drivers or passengers of vehicles with more than three wheels | Reduction in speeding | Intervention lasting three months or more | Moderate |
| 28 | The effect of traffic calming on pedestrian injuries and motor vehicle collisions in two areas of the eThekwini Municipality: a before-and- after study | S Afr Med J 2013; 103 (9): 621-625 | N. Nadesan-Reddy & S. Knigh | South Africa | Interrupted time series | Multi- intervention | All types of users | Reduction in road traffic fatalities, in crash cases, in the severity | Intervention lasting three months or more | Moderate |
| 29 | Urban pedestrian accidents and the efficacy of a counter- measure | Cent Afr J Med 1985 Mar; 31 (3): 62-65 | S. E. Asogwa & C. N. Obionu | Nigeria | quasi experimental no-randomized | Multi- intervention | Pedestrians | Reduction in road traffic fatalities | Intervention lasting three months or more | High |