Parameter

Adolescents during

Growth Hormone Therapy

n = 14

Same Adolescents

after Cessation

n = 14

Age [years]

17.2 ± 2.1

female/male

9/5

GHD/SGA

11/3

ADHD

4

Birth weight [g]

2779 ± 972

Height [cm]

161.3 ± 8.6

Height SDS

−1.44 ± 0.59

BMI [kg/m²]

21.3 ± 2.8

BMI Percentile [%]

53 ± 28

Mean ± SD

Mean ± SD

P-value

Heart Rate [bpm]

84.9 ± 6.2

79.4 ± 8.5*

0.048

HR day [bpm]

93.6 ± 6.6

88.8 ± 10.2

HR night [bpm]

71.8 ± 6.8

64.3 ± 7.0**

0.0013

RMSSD [ms]

39.6 ± 9.9

42.4 ± 11.5

pNN50 [%]

20.6 ± 9.3

22.3 ± 10.3

SDNN [ms]

150.6 ± 27.2

180.6 ± 33.8**

0.0018

Total Power [ms²]

5019 ± 1845

5757 ± 2582

Very Low Frequency [ms²]

2865 ± 1144

3388 ± 1717

Low Frequency [ms²]

1377 ± 655

1596 ± 774

High Frequency [ms²]

698 ± 213

707 ± 267

HF/LF Ratio

0.558 ± 0.204

0.488 ± 0.211