Parameter

Healthy Control

Symptomatic Short Stature (Adolescents)

Growth Hormone Therapy

Untreated

N = 58

N = 30

N = 10

Age [years]

12.8 ± 1.7

13.0 ± 2.0

13.1 ± 2.1

Heart Rate [bpm]

80.8 ± 8.7

85.5 ± 7.5*

0.013

88.72 ± 10.5**

0.0119

HR day [bpm]

89.4 ± 14.6

94.2 ± 7.5

n.s.

98.0 ± 12.4

n.s.

HR night [bpm]

67.0 ± 8.4

73.2 ± 9.9**

0.0028

74.1 ± 9.2*

0.0169

RMSSD [ms]

47.4 ± 12.2

38.5 ± 11.7**

0.0015

37.2 ± 13.8*

0.0119

pNN50 [%]

27.1 ± 10.5

19.6 ± 11.0**

0.0029

19.4 ± 11.5

n.s.

SDNN [ms]

181.1 ± 44.9

148.1 ± 38.0***

0.0009

138.5 ± 25.8**

0.005

Total Power [ms²]

6551 ± 3096

5322 ± 2365

n.s.

4954 ± 3272

n.s.

Very Low Frequency [ms²]

3949 ± 2549

3079 ± 2549

n.s.

2671 ± 2222

n.s.

Low Frequency [ms²]

1676 ± 616

1494 ± 762

n.s.

1341 ± 800

n.s.

High Frequency [ms²]

857 ± 331

674 ± 286*

0.0133

848 ± 782

n.s.