| Parameter | Healthy Control | Symptomatic Short Stature (Adolescents) | ||
|
|
| Growth Hormone Therapy | Untreated | |
| N = 58 | N = 30 | N = 10 | ||
|
| Mean ± SD | Mean ± SD | P-value | |
| Age [years] | 12.8 ± 1.7 | 13.0 ± 2.0 | 13.1 ± 2.1 | n.s. |
| female/male |
| 12/18 | 3/7 | n.s. |
| GHD/SGA |
| 23/7 | 2/8 | n.s. |
| ADHD |
| 9 | 6 | n.s. |
| Height [cm] |
| 149.6 ± 12.1 | 140.7 ± 10.8* | 0.045 |
| Height SDS |
| −1.3 ± 0.8 | −2.1 ± 0.7** | 0.0039 |
| BMI [kg/m2] |
| 18.9 ± 2.6 | 20.3 ± 4.2 | n.s. |
| BMI Percentile [%] |
| 46 ± 29 | 57 ± 36 | n.s. |
| NT-Pro-BNP [0.0 - 85.0 pg/ml] |
| 34 ± 21 | 44 ± 49 | n.s. |
| IgF 1 [57 - 305 µg/ml] |
| 414.9 ± 155.9 | 138.0 ± 91.1** | 0.0011 |
| IgFBP 3 [2100 - 5600 µg/ml] |
| 5167 ± 933 | 3456 ± 861** | 0.0017 |