Glomeruli | Light microscopy: Enlarged glomeruli normal glomerular cellularity increased number of capillary loops diffusely thickened capillary walls double contours of glomerular basement membrane cellular interposition between the glomerular basement membrane and endothelial cells central mesangiolysis Immunofluorescence: Negative (no immune complex deposites) Electron microscopy: Lucent flocculent material between the endothelial cells of glomerular capillary and the glomerularbasement membrane |
Tubules | Atrophied Thyroidization |
Interstitium | Fibrosis |
Intrarenal Vessels | Grade 1: Endothelial swelling mild fibrous arterial intimal thickening and/or mild patchy arteriolar hyalinosis Grade 2: Moderate fibrous arterial intimal thickening or moderate arteriolar hyalinosis Grade 3: Severe occlusive intimal thickening, thrombosis |