Age

FSCC

Wrinkles

Pigmented Spots

Roughness

Hydration

Redness

2006

40.346 ± 14.198

45.444 ± 6.185

18.120 ± 9.040

25.689 ± 10.552

26.232 ± 11.411

54.182 ± 11.312

14.652 ± 2.322

2016

50.346 ± 14.198

48.501 ± 6.911

31.713 ± 17.180

33.410 ± 16.918

36.680 ± 18.422

45.628 ± 9.933

15.045 ± 3.186

∆2016-2006

10.000

3.057 ± 6.918

13.590 ± 15.869

7.71 ± 14.881

10.48 ± 13.520

−10.554 ± 10.635

0.393 ± 2.699

Sig.

P < 0.01

P < 0.01

P < 0.01

P < 0.01

P < 0.01

P < 0.01

P = 0.045