Entry

Mole ratio of d1/d2

N₂ condition

solvent

Temp (˚C)

Time (h)

Yield %

1

1/0.5

N₂

CH₃CN

r.t

10

36

2

1/0.6

N₂

CH₃CN

r.t

10

70

3

1/0.65

N₂

CH₃CN

r.t

6

92

4

1/0.65

--

CH₃CN

r.t

6

0

5

1/0.7

N₂

CH₃CN

r.t

6

35

6

1/0.65/2 equiv NaOAc

N₂

CH₃CN

r.t

10

20

7

1/0.65/2 equiv Cu (OAc)₂

N₂

CH₃CN

r.t

48

60

8

1/0.65/2 equiv CuCl

N₂

CH₃CN

r.t

6

Trace

9

1/0.65

N₂

THF

r.t

10

20

10

1/0.65

N₂

CH₂Cl₂

r.t

12

0

11

1/0.65/2 equiv CuCl

N₂

THF

r.t

10

0

12

1/0.65/2 equiv Cu (OAc)₂

N₂

THF

r.t

10

Trace