Variable

Adjusted OR (95% CI)

Adjusted P-value

More than 3 episodes of acute chest syndrome

1.528 (0.195 - 8.956)

0.686

History of acute chest syndrome in the past 2 weeks.

5.545 (2.210 - 9.911)

0.001

Low steady state haemoglobin (<5 g/dl)

1.953 (0.983 - 3.881)

0.056

High steady state leucocytes (>16,000)

11.284 (5.728 - 13.292)

0.001

Prior TIA

9.102 (3.362 - 15.462)

0.001

Previous stroke

6.712 (1.807 - 8.933)

0.004