Patients

Controls

(n = 73)

(n = 81)

p

Gender**

Male

42 (57.5)

39 (48.1)

0.24#

Female

31 (42.5)

42 (51.9)

Present age (year)***

13 (7 - 18)

10 (8 - 19)

0.13##

Age at diagnosis (year)***

4.5 (0.5 - 14)

-

-

Duration after completion of treatment (year)***

6.5 (0.5 - 13)

-

-

Treatment**

Chemotherapy only

40 (54.8)

-

-

Chemotherapy + radiation†

8 (11.0)

-

-

Chemotherapy + HSCT

5 (6.8)

-

-

Chemotherapy + radiation‡ + HSCT

20 (27.4)

-

-

Diagnosis**

Acute lymphoblastic leukemia

46 (63.0)

-

-

Acute myeloid leukemia

4 (5.5)

-

-

Lymphomaa

8 (11.0)

-

-

Langerhans cell histiocytosis

3 (4.1)

-

-

Brain tumor

5 (6.8)

-

-

Othersb

7 (9.6)

-

-

Recurrence**

14 (19.2)

-

-