Variables

N (%) Wave 4

N (%) Wave 1

N (%) Wave 2

P value (OR [IC 95%])

Comorbidities

Presence

3 (17.6)

3 (17.6)

11 (64.7)

0.072 (4.25 [0.99 - 18.32])

Absence

7 (4.8)

26 (17.8)

113 (77.4)

0.072 (0.24 [0.06 - 1.01])

Symptoms

Asthenia

3 (3.5)

11 (12.8)

72 (83.7)

0.26 (0.97 [0.93 - 1.00])

Rhinorrhea

1 (4.5)

6 (27.3)

15 (68.2)

0.37 (3.07 [0.27 - 35.39])

Cough

2 (6.7)

7 (23.3)

21 (70)

0.10 (18.25 [1.36 - 245.19])

Abdominal pain

0 (0)

7 (9.7)

65 (90.3)

0.25 (1.04 [0.99 - 1.08])

Diarrhea

3 (43)

6 (8.6)

61 (87.1)

0.09 (0.96 [0.91 - 1.00])

Physical signs

Skin rash

1 (20)

1 (20)

3 (60)

0.10 (18.25 [1.35 - 245.18])

Tachycardia

0 (0)

9 (25.7)

26 (74.3)

1.00 (1.02 [0.99 - 1.04])

Tachypnea

1 (1.7)

16 (27.1)

42 (71.2)

0.39 (0.99 [0.95 - 1.01])

High blood pressure

0 (0)

2 (12.8)

9 (81.8)

1.00 (1.01 [0.99 - 1.02])

Low oxygen saturation

1 (16.7)

2 (33.3)

3 (50)

0.04 (0.83 [0.59 - 1.18])

Clinical stages

Severe/Critical

3 (9.4)

7 (21.9)

22 (68.8)

0.14 1.83 (0.45 - 7.52)

Moderate

1 (0.8)

22 (17.6)

102 (81.6)

0.00 (0.026 [0.00 - 0.21])

Asymptomatic and mild

6 (100)

0 (0)

0 (0)

0.00 (39.25 [14.92 - 103.27])