| Parameter/ Duration | Placebo | Vitamin C | Zinc | Omega 3 Fatty acid | Combined | |||||
| n | Mean ± SE | n | Mean ± SE | n | Mean ± SE | n | Mean ± SE | n | Mean ± SE | |
| FEV1 (%) Baseline Week 2 Week 6 Week 12 Month 6 Month 12 |
142 138 126 118 105 78 |
76.2 ± 6.8 76.8 ± 2.3 78.9 ± 1.2 79.9 ± 1.5 76.5 ± 5.3 76.9 ± 2.1 |
28 28 25 20 18 15 |
76.2 ± 6.7 77.0 ± 2.1 78.8 ± 1.3 80.1 ± 1.4 80.3 ± 1.2 81.1 ± 2.1 |
32 31 26 22 19 17 |
75.8 ± 5.8 78.9 ± 2.9 80.2 ± 2.1 81.1 ± 2.1 81.3 ± 2.1 81.0 ± 2.2 |
35 35 33 29 24 21 |
76.3 ± 7.2 78.8 ± 3.1 82.3 ± 4.2 85.1 ± 2.6 85.9 ± 2.6 86.1 ± 3.1 |
40 39 35 31 26 28 |
76.1 ± 6.9 79.2 ± 2.5 83.5 ± 1.8 88.2 ± 1.1 88.6 ± 1.3 89.2 ± 1.2 |
| FEV1/FVC Baseline Week 2 Week 6 Week12 Month 6 Month 12 |
142 138 126 118 108 74 |
76.6 ± 1.6 75.3 ± 2.1 75.9 ± 2.4 76.6 ± 1.6 75.8 ± 2.5 76.6 ± 2.1 |
28 28 25 20 19 17 |
77.2 ± 2.3 78.2 ± 2.1 77.9 ± 2.4 81.4 ± 2.5 81.6 ± 3.1 82.1 ± 2.8 |
32 31 26 22 17 19 |
78.2 ± 2.2 79.2 ± 1.9 78.9 ± 2.3 82.4 ± 2.3 80.5 ± 1.9 82.8 ± 2.2 |
35 35 33 29 22 23 |
78.2 ± 2.1 80.2 ± 2.0 79.9 ± 2.2 80.1 ± 1.9 80.3 ± 1.5 82.3 ± 1.4 |
40 39 35 31 25 20 |
77.5 ± 2.8 81.8 ± 1.7 83.2 ± 1.9 82.4 ± 2.1 82.8 ± 1.5 83.1 ± 1.2 |