| Feature | Pituitary cells | Hepatocytes | K cells | Muscle cells | Fibroblasts | BMSCs |
| Endodermal Origin | − | + | + | − | − | − |
| Glucose sensing machinery (i.e. GLUT2 and glucokinase) | − | + | + | − | − | − |
| Glucose-responsive promoters | − | + | + | − | − | − |
| Target of insulin action | − | + | − | + | − | − |
| Regulated secretory pathway (i.e. insulin storage and stimulus-secretion coupling) | + | − | + | − | − | − |
| Processing enzymes (i.e. PC1/3 and PC2) | + | − | + | − | − | − |