Variables

Patients with renal

involvement (n = 287)

Patients without renal

involvement (n = 62)

p-value

Age (years)

64.2 ± 12.2

60.7 ± 14.8

0.045

Gender (M/F)

133/154

32/30

0.451

MPO-positive AAV

262 (91.3%)

54 (87.1%)

0.306

PR3-positive AAV

25 (8.7%)

8 (12.9%)

General manifestation

192 (66.9%)

50 (80.7%)

0.033

Skin involvement

17 (5.9%)

5 (8.1%)

0.733

ENT involvement

8 (2.8%)

7 (11.3%)

0.008

Cardiovascular involvement

105 (36.6%)

7 (11.3%)

<0.001

Abdominal involvement

92 (32.1%)

8 (12.9%)

0.002

Nervous system involvement

28 (9.8%)

11 (17.7%)

0.07

Pulmonary involvement

127 (44.3%)

37 (59.7%)

0.027

Alveolar hemorrhage

41 (14.3%)

7 (11.3%)

0.535

Interstitial lung disease

77 (26.8%)

25 (40.3%)

0.034

Hemoglobin (g/L)

87.0 (73.0, 105.0)

108.5 (95.8, 121.3)

<0.001

Serum albumin (g/L)

29.0 (26.0, 35.0)

33.0 (29.8, 37.0)

<0.001

Complement C3 (g/L)

0.78 (0.64, 0.89)

0.92 (0.79, 1.14)

<0.001

Complement C4 (g/L)

0.22 (0.17, 0.27)

0.23 (0.16, 0.28)

0.963

BVAS

15.0 (12.0, 19.0)

9.0 (8.0, 12.0)

<0.001

Survival

147 (54.7%)

38 (70.4%)

0.033

Death

122 (45.4%)

16 (29.6%)