BDTM

BDEM and bivariate model

Doses (mg/kg)

Posterior probability of target toxicity

[16%, 33%]

using BDTM

Posterior probability of excessive toxicity

[33%, 100%]

using BDTM

Posterior probability of unacceptable activity

[0%, 30%]

using BDEM

Posterior mean of (no toxicity, activity) rate

using bivariate model

1

0.002

0.000

0.998

0.021

3

0.010

0.000

0.239

0.393

5

0.019

0.000

0.000

0.620

10

0.215

0.000

0.000

0.618

15

0.467

0.041

0.088

0.460

20

0.508

0.151

0.548

0.296