| BDTM | BDEM and bivariate model | ||
Doses (mg/kg) | Posterior probability of target toxicity [16%, 33%] using BDTM | Posterior probability of excessive toxicity [33%, 100%] using BDTM | Posterior probability of unacceptable activity [0%, 30%] using BDEM | Posterior mean of (no toxicity, activity) rate using bivariate model |
1 | 0.002 | 0.000 | 0.998 | 0.021 |
3 | 0.010 | 0.000 | 0.239 | 0.393 |
5 | 0.019 | 0.000 | 0.000 | 0.620 |
10 | 0.215 | 0.000 | 0.000 | 0.618 |
15 | 0.467 | 0.041 | 0.088 | 0.460 |
20 | 0.508 | 0.151 | 0.548 | 0.296 |