Kinetic Parameter | Description | Reference |

KAICAR | Michaelis Menten constant of AICAR transformylase converting AICAR to FAICAR | [S1] |

kDHFR | Rate constant of dihydrofolate reductase converting DHF to THF | [S2] |

KDHFR | Michaelis Menten constant for dihydrofolate reductase converting DHF to THF | [S2] |

KFTCD | Michaelis Menten constant for 5-formimino-THF cyclodeaminase converting 5-formimino-THF to 5,10-methenyl-THF | [S3] |

kFTCL | Rate constant of 5-formyl THF cycloligase converting 5-formyl THF to 5,10-methenyl THF | [S4] |

KFTS | Michaelis Menten constant for formyl-THF synthetase converting formate to 10-formyl-THF | [S5] |

KGDC | Michaelis Menten constant for glycine decarboxylase converting THF to 5,10-methylene THF | [S6] |

kGF | Second order conversion rate of glyoxylate to formate | [S7] |

KGFT | Michaelis Menten constant for glutamate formiminotransferase converting formiminoglutamate to 5-formimino-THF | [S8] |

KGSYN | Michaelis Menten constant for glyoxylate synthetase converting formate to glyoxylate | [S9] |

KGTF | Michaelis Menten constant for GAR transformylase converting GAR to FGAR | [S10] |

KKHMT | Michaelis Menten constant for ketopantoate hydroxymethyltransferase converting a-KIVA to THF and ketopantoate | [S11] |

kMHF_GAR | Rate constant for GAR transformylase converting 10-formyl-THF to THF | [S10] |

KMTC | Michaelis Menten constant for 5,10-methylene THF cyclohydrolase converting 5,10-methenyl-THF to 10-formyl-THF | [S12] |

KMTD | Michaelis Menten constant for 5,10-methylene THF dehydrogenase converting 5,10-methylene-THF to 5,10-methenyl-THF | [S12] |

kMTR | Rate constant for methylene THF reductase converting 5,10-methylene-THF to 5-methyl-THF | [S13] |

KMTR | Michaelis Menten constant for methylene THF reductase converting 5,10-methylene-THF to 5-methyl-THF | [S13] |

KMTS | Michaelis Menten constant for methionine synthase converting homocysteine to methionine | [S14] |

kSHM | Rate constant for serine hydroxymethyltransferase converting 5,10-methenyl-THF to 5-formyl-THF | [S15] |

KSHM | Michaelis Menten constant for serine hydroxymethyl transferase converting 5,10-methenyl-THF to 5-formyl-THF | [S15] |

kSHMT | Rate constant for serine hydroxymethyltransferase converting serine to glycine | [S16] |

KSHMT | Michaelis Menten constant for serine hydroxymethyltransferase converting serine to glycine | [S16] |

kTFA | Rate constant for the association of THF and Formaldehyde to 5,10-methylene-THF | [S17] |

kTFD | Rate constant for the dissociation of 5,10-methylene-THF to THF and Formaldehyde | [S17] |

KTS | Michaelis Menten for thymidylate synthase induced synthesis of thymidylate from 5,10-methenyl-THF | [S18] |

VAICAR | Vmax of AICAR transformylase converting AICAR to FAICAR | [S1] |

VFTCD | Vmax for 5-formimino-THF cyclodeaminase converting 5-formimino-THF to 5,10-methenyl-THF | [S3] |

VFTS | Vmax for formyl-THF synthetase converting formate to 10-formyl-THF | [S5] |

VGDC | Vmax for glycine decarboxylase converting THF to 5,10-methylene THF | [S6] |

VGFT | Vmax for glutamate formiminotransferase converting formiminoglutamate to 5-formimino-THF | [S8] |

VGSYN | Vmax for glyoxylate synthetase converting formate to glyoxylate | [S9] |

VGTF | Vmax for GAR transformylase converting GAR to FGAR | [S10] |

VKHMT | Vmax for ketopantoate hydroxymethyltransferase converting a-KIVA to THF and ketopantoate | [S34] |