Type of activity

Part used

Extract

Dose

Model

Key result

Ref

Anti-inflammatory activity

Leaves

Methanolic extract

1 to 100 mg/kg i.p.

In vivo

Significant inhibition of rat paw edema.

[16]

5 mg/kg i.p.

In vivo

Substantial anti-inflammatory activity in case of carrageenan- tempted edema in rats.

[16]

Anti-leishmanial activity

Leaves

2-Benzoxazolinone (BOA)

0.25 - 1 g/kg i.p.

In vitro

Anti-leishmanial activity against Leishmania donovani.

[15]

Osteoblastic activity

Leaves

Methanolic extract

In vivo

Increased the growth and differentiation of osteoblasts significantly, indicating that A. ilicifolius leaves may help to prevent osteoporosis.

[18]

Hepatoprotective activity

Leaves

Alcoholic extract

250 and 500 mg/kg

In vivo

Significantly reduced CCl4- induced hepatotoxicity in rats.

[19]

Anticancer activity

Leaves

Alcoholic extract

250, 500 mg/kg

In vivo

Effective against tumor progression and carcinogen induced skin papilloma formation in mice, in reduction of tumor volume & cytotoxic against lung fibroblast cells in mice.

[19]

Antiulcer activity

Leaves

Methanolic extracts

doses of 100, 20

mg/kg body weight

In vivo

Significant inhibition of gastric lesions induced by pylorus ligation and ethanol-induced gastric ulcers.

[20]

Antimicrobial activity

Leaves, stem, and root

Ethanol, methanol, and aqueous extracts

10 mg/ml

In vitro

Strong inhibitory action against Bacillus subtilis, Staphylococcus aureus, Candida albicans, Aspergillus fumigatus, and Aspergillus niger and moderate inhibitory action against Pseudomonas aeruginosa and Proteus vulgaris.

[21] [24]

Cytotoxic

activity

Flowers

Methanolic crude extract

LC50 value at 60 μg/ml and LC90 value at 120 μg/ml

In vitro

Cytotoxic activity.

[22]

Antioxidant

activity

Flowers

Methanol extract, acetone, acetone 70%, methanol 80% and water

500 μg/ml to 0.98 μg/ml. IC50 was recorded 5.1 μg/ml.

In vitro

free radical scavenging activity.

[23]

Leaves

Alcoholic Extract

IC50 of 550 µg/ml, 2750 µg/ml, 600 & 670 µg/ml

In vitro

Inhibition of formation of oxygen derived free radicals, superoxide radicals, nitric oxide radical.

[23]