Type of activity | Part used | Extract | Dose | Model | Key result | Ref |
Anti-inflammatory activity | Leaves | Methanolic extract | 1 to 100 mg/kg i.p. | In vivo | Significant inhibition of rat paw edema. | [16] |
5 mg/kg i.p. | In vivo | Substantial anti-inflammatory activity in case of carrageenan- tempted edema in rats. | [16] | |||
Anti-leishmanial activity | Leaves | 2-Benzoxazolinone (BOA) | 0.25 - 1 g/kg i.p. | In vitro | Anti-leishmanial activity against Leishmania donovani. | [15] |
Osteoblastic activity | Leaves | Methanolic extract |
| In vivo | Increased the growth and differentiation of osteoblasts significantly, indicating that A. ilicifolius leaves may help to prevent osteoporosis. | [18] |
Hepatoprotective activity | Leaves | Alcoholic extract | 250 and 500 mg/kg | In vivo | Significantly reduced CCl4- induced hepatotoxicity in rats. | [19] |
Anticancer activity | Leaves | Alcoholic extract | 250, 500 mg/kg | In vivo | Effective against tumor progression and carcinogen induced skin papilloma formation in mice, in reduction of tumor volume & cytotoxic against lung fibroblast cells in mice. | [19] |
Antiulcer activity | Leaves | Methanolic extracts | doses of 100, 20 mg/kg body weight | In vivo | Significant inhibition of gastric lesions induced by pylorus ligation and ethanol-induced gastric ulcers. | [20] |
Antimicrobial activity | Leaves, stem, and root | Ethanol, methanol, and aqueous extracts | 10 mg/ml | In vitro | Strong inhibitory action against Bacillus subtilis, Staphylococcus aureus, Candida albicans, Aspergillus fumigatus, and Aspergillus niger and moderate inhibitory action against Pseudomonas aeruginosa and Proteus vulgaris. | [21] [24] |
Cytotoxic activity | Flowers | Methanolic crude extract | LC50 value at 60 μg/ml and LC90 value at 120 μg/ml | In vitro | Cytotoxic activity. | [22] |
Antioxidant activity | Flowers | Methanol extract, acetone, acetone 70%, methanol 80% and water | 500 μg/ml to 0.98 μg/ml. IC50 was recorded 5.1 μg/ml. | In vitro | free radical scavenging activity. | [23] |
Leaves | Alcoholic Extract | IC50 of 550 µg/ml, 2750 µg/ml, 600 & 670 µg/ml | In vitro | Inhibition of formation of oxygen derived free radicals, superoxide radicals, nitric oxide radical. | [23] |