Sex

Dose (mg/kg)

ALT (U/L)

AST (U/L)

Bilirubin (mg/dl)

Serum proteins (mg/dl)

Males

Control

12.47 ± 1.36

52.39 ± 7.93

0.02 ± 0.01

5.92 ± 0.28

250

6.92 ± 1.33^***

47.86 ± 7.48^ns

0.00 ± 0.00^ns

5.12 ± 0.04^***

500

6.52 ± 1.62^***

31.11 ± 4.32^***

0.00 ± 0.00^ns

5.06 ± 0.04^***

10000

4.67 ± 0.82^***

35.75 ± 3.00^**

0.00 ± 0.00^ns

5.15 ± 0.04^***

Satellite

12.06 ± 2.33^ns

27.58 ± 3.94^***

0.00 ± 0.00^ns

5.25 ± 0.05^***

Females

Control

10.36 ± 1.44

44.64 ± 1.48

0.00 ± 0.00

5.55 ± 0.04

250

4.80 ± 0.87^***

27.14 ± 3.57^***

0.00 ± 0.00^ns

5.12 ± 0.03^***

500

5.55 ± 0.85^***

28.53 ± 1.72^***

0.00 ± 0.00^ns

5.03 ± 0.04^***

1000

5.86 ± 0.82^***

29.41 ± 3.12^***

0.00 ± 0.00^ns

5.05 ± 0.02^***

Satellite

9.84 ± 1.82^ns

22.02 ± 3.18^***

0.00 ± 0.00^ns

5.20 ± 0.01^***