Dose (mg/kg)

Control

250

500

1000

Satellite

Female

WBC (10³/µL)

7.36 ± 0.67

6.78 ± 1.06^ns

9.91 ± 1.27^ns

9.73 ± 2.42^ns

3.31 ± 0.18^**

RBC (10⁶/µL)

6.01 ± 0.07

6.69 ± 0.48^*

6.34 ± 0.17^ns

6.29 ± 0.19^ns

6.57 ± 0.35^ns

Hematocrit (%)

44.50 ± 4.65

42.68 ± 2.80^ns

40.20 ± 1.41^ns

39.83 ± 1.20^ns

43.57 ± 1.27^ns

Platelets (10³/µL)

690.00 ± 105.4

846.00 ± 89.71^*

874.00 ± 71.05^*

937.80 ± 58.04^**

839.80 ± 59.25^ns

Haemoglobin (g/dL)

12.50 ± 0.29

13.63 ± 0.74^*

13.20 ± 0.40^ns

13.20 ± 0.40^ns

13.58 ± 0.51^*

Granulocytes (%)

7.77 ± 0.28

21.20 ± 2.84^***

15.98 ± 0.65^***

22.80 ± 3.44^***

8.00 ± 0.21^ns

Lymphocytes (%)

95.60 ± 2.44

74.40 ± 3.17^***

83.20 ± 3.75^***

75.68 ± 7.94^***

91.48 ± 0.28^ns

MID (%)

1.35 ± 0.56

4.40 ± 0.48^***

3.05 ± 0.10^***

5.02 ± 0.66^***

0.95 ± 0.12^ns

MCHC (g/dl)

29.78 ± 2.87

31.90 ± 0.64^ns

32.87 ± 0.20^*

3.23 ± 0.69^ns

32.03 ± 0.26^ns

MCV (fl)

78.60 ± 1.84

64.90 ± 5.02^***

77.15 ± 1.14^ns

61.07 ± 1.85^***

64.03 ± 0.61^***

MCH (pg)

20.80 ± 0.50

20.30 ± 0.82^ns

20.45 ± 0.23^ns

19.65 ± 0.20^*

20.80 ± 0.50^ns

RDW-CV (%)

19.30 ± 1.53

17.58 ± 1.72^ns

18.28 ± 2.70^ns

16.53 ± 1.03^ns

16.50 ± 0.64^ns

RDW-SD (fl)

33.78 ± 2.40

32.83 ± 1.02^ns

31.50 ± 1.22^ns

33.00 ± 2.56^ns

35.35 ± 2.13^ns

MPV (fl)

7.80 ± 0.86

7.77 ± 0.46^ns

7.45 ± 0.64^ns

7.95 ± 0.71^ns

7.92 ± 0.50^ns

PDW (fl)

16.03 ± 0.09

15.70 ± 0.08^*

15.95 ± 0.26^ns

15.70 ± 0.08^*

15.98 ± 0.17^ns

PCT (%)

0.53 ± 0.09

0.65 ± 0.11^ns

0.59 ± 0.13^ns

0.49 ± 0.12^ns

0.72 ± 0.11^ns

P-LCC

130.30 ± 21.42

109.00 ± 22.46^ns

126.30 ± 3.09^ns

119.3 ± 10.63^ns

137.80 ± 7.71^ns

P-LCR

16.23 ± 1.11

18.28 ± 5.49^ns

17.23 ± 2.69^ns

19.68 ± 3.54^ns

17.98 ± 4.11^ns