Minor criteria |
● Predisposition, predisposing heart condition or injection drug use ● Fever, temperature > 38˚C ● Vascular phenomena, major arterial emboli, septic pulmonary infarcts, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages and Janeway’s lesions ● Immunologic phenomena: glomerulonephritis, Osler’s nodes, Roth’s spots and rheumatoid factor ● Microbiological evidence: positive blood culture but does not meet a major criterion as noted above * or serological evidence of active infection with organism consistent with IE |
Interpretation |
Definite infective endocarditis: Pathological criteria ● Microorganism: demonstrated by culture or histology in a vegetation or in a vegetation that has embolized, or in a intracardiac abscess or ● Pathologic lesions: vegetation or intracardiac abscess present confirmed by histology showing active endocarditis Clinical criteria: ● 2 major criteria, or ● 1 major and 3 minor, ● or 5 minor Possible infective endocarditis ● 1 major and 1 minor, or ● 3 minor ● Rejected Diagnosis of infective endocarditis is rejected ● Firm alternate diagnosis explaining evidence of infective endocarditis, or ● Resolution of infective endocarditis syndrome, with antibiotic therapy for 4 days or less, or ● No pathologic evidence of infective endocarditis at surgery or autopsy, with antibiotic therapy for 4 days or less |