CRP > 100 mg/l or more than 50 mg/l that has doubled in the last 48 hours

Lymphocyte recount < 0.6 × 109

Interleukin-6 (IL-6) > 3 its normal limit

Ferritin > 300 µg/L

DHL > 250 U/L

D dimer > 1 µg/L.