Outcome

Bivariate

Multivariate^¶

Point estimate

p-value

Point estimate

p-value

Lung function

FEV₁ percent predicted

0.57

0.75

0.75

0.57

FEV₁/FVC

−0.81

0.40

−0.87

0.36

Symptoms/quality of life

BCSS⁺

0.22

0.06

0.04

0.26

SGRQ⁺

0.01

0.92

0.01

0.9

Biologic markers

WBC (/mm³)

316

<0.01

324

<0.01

Neutrophils (/mm³)

726

0.02

692

0.05

Lymphocytes (/mm³)

304

0.01

293

0.03

Eosinophils (/mm³)

0.26

0.05

0.14

0.26

Hemoglobin (g/dL)

0.32

0.03

0.23

0.07

Platelets (K/mm³)

3.43

0.56

4.86

0.39

Fibrinogen⁺ (mg/dL)

0.01

0.93

0.18

0.66

ENO⁺ (ppb)

−0.17

0.09

-0.13

0.23