Intensification therapy protocol (LAL GFAOP 2019)

Medicines

Doses

Days

Vincristine

1.5 mg/m²

J1, J8, J15

Dexamethasone

10 mg/m²

D1 - D15 then decrease and stop in 1 week

Adriamycin

25 mg/m²

J1, J8, J15

L-asparaginase

6000 IU/m² not to exceed 10,000 IU/injections

J3, J5, J8, J10, J12, J15

Intrathecal methotrexate

15 mg

J1