| Factors | n | Cause of death | p | |||
| Brain metastasis | Other sites metstasis | |||||
| (n = 30) | (n = 5) | |||||
| No. | % | No. | % | |||
| Age (mean) | 56.9 (30.8 - 82.3) | 57.1 (49.7 - 63.6) | 0.96 | |||
| Pathological type | ||||||
| Ductal carcinoma | 28 | 23 | 76.7 | 5 | 100.0 | 0.11 |
| Other | 7 | 7 | 23.3 | 0 | 0.0 | |
| Nuclear grade | ||||||
| 1/2 | 19 | 15 | 65.2 | 4 | 80.0 | 0.50 |
| 3 | 9 | 8 | 34.8 | 1 | 20.0 | |
| Estrogen receptor | ||||||
| Negative | 25 | 23 | 76.7 | 2 | 40.0 | 0.06 |
| Positive | 10 | 7 | 23.3 | 3 | 60.0 | |
| HER-2/NEU | ||||||
| Negative | 14 | 12 | 40.0 | 2 | 30.0 | 1.00 |
| Positive | 21 | 18 | 60.0 | 3 | 70.0 | |
| Tumor size | ||||||
| T1 | 4 | 3 | 9.7 | 1 | 10.0 | 0.54 |
| T2-4 | 31 | 27 | 90.3 | 4 | 90.0 | |
| Lymph node metastasis | ||||||
| Negative | 10 | 9 | 10.0 | 1 | 20.0 | 0.64 |
| Positive | 25 | 21 | 90.0 | 4 | 80.0 | |
| Stage | ||||||
| 2 | 17 | 15 | 50.0 | 2 | 40.0 | 0.23 |
| 3 | 12 | 9 | 30.0 | 3 | 60.0 | |
| 4 | 6 | 6 | 20.0 | 0 | 0.0 | |
| Number of brain metastasis | ||||||
| 1 | 9 | 7 | 23.3 | 2 | 40.0 | 0.44 |
| 1< | 26 | 23 | 76.7 | 3 | 60.0 | |
| ECOG PS | ||||||
| 0 - 1 | 16 | 14 | 46.7 | 2 | 40.0 | 0.78 |
| 2 - 4 | 19 | 16 | 53.3 | 3 | 60.0 | |
| Therapy of brain metastasis | ||||||
| Whole brain radiotherapy | ||||||
| + | 31 | 27 | 90.0 | 4 | 80.0 | 0.54 |
| − | 4 | 3 | 30.0 | 1 | 20.0 | |
| Tumorectomy | ||||||
| + | 2 | 0 | 0.0 | 2 | 40.0 | 0.003 |
| − | 33 | 30 | 100.0 | 3 | 60.0 | |
| Systemic therapy | ||||||
| + | 16 | 13 | 43.3 | 3 | 60.0 | 0.49 |
| − | 19 | 17 | 56.7 | 2 | 20.0 | |