Patient

Cytotoxic chemotherapy

Daily dose Duration

Capecitabine

Oxaliplatin

5-fluorouracil

Methotrexate

FOLFOX

FOLFIRI

4

Standard regimen 4.5 m

6

3.5 m

3.5 m

9

2000 m/7.5m daily

10

Standard regimen 3 m

11

1500 mg/3m daily

14

1500 mg/2m daily

85 mg/m2