ALP (U/L)

100 - 325

LC-Plasma

20

169.0 ± 41.6

0.048

174.8 ± 38.6

0.045

0.113

167.7 ± 40.9

0.020

0.715

162.9 ± 39.8

0.011

0.019

Placebo

20

200.0 ± 53.2

206.7 ± 57.1

0.032

206.4 ± 58.0

0.123

204.6 ± 57.6

0.195

γ-GT (γ-GTP) (U/L)

M: ≤80 F: ≤30

LC-Plasma

20

19.3 ± 9.4

0.954

18.7 ± 7.8

0.517

0.323

17.3 ± 7.7

0.332

0.059

17.8 ± 6.8

0.304

0.091

Placebo

20

19.1 ± 6.5

20.2 ± 6.7

0.346

20.2 ± 10.4

0.565

21.6 ± 15.1

0.435

CK (CPK) (U/L)

M: 60 - 270 F: 40 - 150

LC-Plasma

20

117.6 ± 63.0

0.057

138.3 ± 127.1

0.421

0.516

173.4 ± 228.3

0.220

0.303

117.8 ± 66.1

0.573

0.984

Placebo

20

86.2 ± 31.9

112.3 ± 66.0

0.014

106.3 ± 75.6

0.179

143.7 ± 192.5

0.175

Fasting blood glucose (mg/dL)

70 - 109

LC-Plasma

20

83.6 ± 7.2

0.468

82.1 ± 6.2

0.593

0.260

79.5 ± 9.0

0.370

0.005

79.5 ± 9.3

0.350

0.025

Placebo

20

82.1 ± 6.2

81.0 ± 6.7

0.315

81.7 ± 6.1

0.704

81.8 ± 6.2

0.791

HbA1c (%)

4.6 - 6.2

LC-Plasma

20

5.4 ± 0.3

0.356

5.3 ± 0.3

0.859

0.004

5.4 ± 0.3

0.297

1.000

5.4 ± 0.3

0.613

0.104

Placebo

20

5.3 ± 0.3

5.3 ± 0.3

0.481

5.3 ± 0.3

0.629

5.4 ± 0.3

0.007

Total protein (mg/dL)

120 - 219

LC-Plasma

20

196.4 ± 25.7

0.839

202.9 ± 23.8

0.612

0.120

193.7 ± 19.4

0.877

0.431

193.5 ± 20.5

0.896

0.433

Placebo

20

198.3 ± 31.1

198.6 ± 29.7

0.938

195.0 ± 32.0

0.361

194.7 ± 33.3

0.275

LDL-cholesterol (mg/dL)

65 - 139

LC-Plasma

20

114.7 ± 24.1

0.617

118.1 ± 19.5

0.265

0.339

112.7 ± 16.8

0.488

0.482

112.5 ± 18.1

0.610

0.458

Placebo

20

110.9 ± 24.2

110.5 ± 22.8

0.895

108.2 ± 23.3

0.332

109.0 ± 24.4

0.528

HDL-cholesterol (mg/dL)

M: 40 - 85 F: 40 - 95

LC-Plasma

20

63.4 ± 12.4

0.266

62.3 ± 14.0

0.349

0.374

61.1 ± 11.5

0.134

0.057

60.1 ± 12.0

0.055

0.008

Placebo

20

68.8 ± 17.7

66.8 ± 15.9

0.176

67.6 ± 15.1

0.442

69.3 ± 16.9

0.805

Triglyceride (TG) (mg/dL)

30 - 149

LC-Plasma

20

74.7 ± 31.5

0.950

76.5 ± 25.4

0.639

0.706

74.0 ± 28.2

0.878

0.901

83.4 ± 39.8

0.398

0.188

Placebo

20

74.0 ± 37.7

71.9 ± 34.8

0.649

75.8 ± 41.9

0.728

72.7 ± 39.0

0.892

Total protein (g/dL)

6.7 - 8.3

LC-Plasma

20

7.1 ± 0.4

0.058

7.2 ± 0.4

0.430

0.138

7.1 ± 0.3

0.473

0.938

7.1 ± 0.4

0.001

0.353

Placebo

20

7.3 ± 0.4

7.3 ± 0.4

0.214

7.2 ± 0.5

0.056

7.5 ± 0.4

0.034

Albumin (g/dL)

3.8 - 5.2

LC-Plasma

20

4.5 ± 0.2

0.790

4.5 ± 0.3

0.521

0.356

4.5 ± 0.2

0.473

0.643

4.4 ± 0.3

0.385

0.004

Placebo

20

4.5 ± 0.2

4.5 ± 0.3

0.761

4.4 ± 0.3

0.209

4.5 ± 0.3

1.000

Urea nitrogen (mg/dL)

8.0 - 20.0

LC-Plasma

20

13.6 ± 2.9

0.519

12.7 ± 2.7

0.610

0.089

13.2 ± 3.0

0.402

0.524

12.8 ± 3.5

0.469

0.244

Placebo

20

13.0 ± 3.1

12.3 ± 2.4

0.133

14.0 ± 3.1

0.158

13.5 ± 2.0

0.431

Creatinine (mg/dL)

M: 0.61 - 1.04 F: 0.47 - 0.79

LC-Plasma

20

0.79 ± 0.17

0.618

0.79 ± 0.18

0.830

0.934

0.73 ± 0.16

0.965

0.000

0.77 ± 0.17

0.591

0.144

Placebo

20

0.76 ± 0.14

0.77 ± 0.12

0.227

0.74 ± 0.11

0.123

0.74 ± 0.13

0.084

Uric acid (mg/dL)

M: 3.8 - 7.0 F: 2.5 - 7.0

LC-Plasma

20

5.6 ± 1.1

0.187

5.4 ± 1.4

0.416

0.287

5.7 ± 1.2

0.632

0.642

5.6 ± 1.3

0.345

0.750

Placebo

20

5.1 ± 0.9

5.1 ± 0.8

0.756

5.5 ± 0.9

0.001

5.3 ± 0.9

0.200

Sodium (Na) (mEq/L)

137 - 147

LC-Plasma

20

140.6 ± 2.0

0.928

140.9 ± 1.4

0.151

0.554

140.8 ± 1.7

0.503

0.640

141.3 ± 2.1

0.486

0.049

Placebo

20

140.6 ±

141.6 ± 1.4

0.016

141.2 ± 1.6

0.083

141.7 ± 1.5

0.010

Chloride (Cl) (mEq/L)

98 - 108

LC-Plasma

20

103.9 ± 1.3

1.000

104.6 ± 2.0

0.735

0.126

104.0 ± 2.3

0.096

0.913

105.2 ± 2.0

1.000

0.006

Placebo

20

103.9 ± 1.7

104.8 ± 1.7

0.028

105.1 ± 1.8

0.013

105.2 ± 1.3

0.001

Potassium (K) (mEq/L)

3.5 - 5.0

LC-Plasma

20

4.3 ± 0.4

0.459

4.3 ± 0.3

0.166

0.605

4.3 ± 0.4

0.458

0.753

4.4 ± 0.2

0.408

0.217

Placebo

20

4.3 ± 0.1

4.2 ± 0.2

0.470

4.3 ± 0.2

0.691

4.3 ± 0.1

0.026

Calcium (Ca) (mg/dL)

8.4 - 10.4

LC-Plasma

20

9.5 ± 0.3

0.816

9.5 ± 0.3

0.743

0.357

9.5 ± 0.3

0.251

0.597

9.5 ± 0.3

0.780

0.500

Placebo

20

9.5 ± 0.3

9.4 ± 0.4

0.199

9.4 ± 0.4

0.087

9.5 ± 0.4

0.814