Angiogenesis-related factors

Osteogenesis-related factors

HIF-1α (pg/mL)

VEGF (pg/mL)

BMP2 (ng/mL)

Osterix (ng/mL)

Control

1.00 ± 0.08

1.00 ± 0.07

1.00 ± 0.07

1.00 ± 0.09

Model

0.31 ± 0.02*

0.31 ± 0.01*

0.36 ± 0.02*

0.42 ± 0.02*

Inhibitor

0.22 ± 0.02*^#

0.23 ± 0.01*^#

0.12 ± 0.01*^#

0.22 ± 0.01*^#

TCM

0.48 ± 0.03*^#

0.66 ± 0.02*^#

0.74 ± 0.02*^#

0.75 ± 0.02*^#

Inhibitor + TCM

0.37 ± 0.03^&

0.44 ± 0.06^&

0.53 ± 0.06^&

0.65 ± 0.08^&

F value

384.79

628.55

153.74

330.36

P value

0.00

0.00

0.00

0.00