Light Microscopic Finding

Age of Scald Injury

Group II

after 2 Days

Group III

after 7 Days

Group IV

after 1 Month

Group V

after 3 Months

Destruction of Adnexal Structures

+

++

+

+

Ulceration in the Epidermis

+

++

+

−

Inflammatory Infiltrate in the Dermis

++

+++

−

−

Deposition of Multiple Collagen Layers

−

−

++

+++

Re-epithelialization

−

−

+

+++

Multiple Cell Islands

−

−

++

++

Epithelial Cell Migration to the Scald

−

−

+

++

TNF-α Immunoexpression

+++

++

−

−