A. Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC? If yes: proceed If no: do not use this algorithm |
B. Order global coagulation tests: PT, platelet count, fibrinogen, fibrin related marker |
C. Score the test results 1) Platelet count (≥100 × 109/l = 0, <100 × 109/l = 1, <50 × 109/l = 2) 2) Elevated fibrin marker (e.g. D-dimer, fibrin degradation products) (no increase = 0, moderate increase = 2, strong increase = 3) 3) Prolonged PT (<3 s = 0, >3 but <6 s = 1, >6 s = 2) 4) Fibrinogen level (>1 g/l = 0, <1 g/l = 1) |
D. Calculate score: ≥5: compatible with overt DIC, repeat score daily <5: suggestive for non-overt DIC, repeat next 1 - 2 d |