| 1. HD+CLOSE (n = 16) | 2. HD+DISTANT (n = 16) | 3. HD− (n = 38) | Group comparisons Pa | ||||||||||
n | M | SD | n | M | SD | n | M | SD | 1 - 3 | 2 - 3 | 1 - 2 | |||
Gender of affected parentb (male/female) | 8/8 | 50% |
| 11/5 |
|
| 14/22c |
|
| 0.454 | 0.047* | 0.280 | ||
Age of onset of affected parenta |
| 43.4 | (12.2) |
| 49.3d | (11.0) |
| 47.0e | (10.6) | 0.272 | 0.791 | 0.237 | ||
CAG length of wildtype allelea |
| 18.8t | (2.0) |
| 18.3 | (3.2) |
| 20.7g | (3.9) | 0.091 | 0.035* | 0.577 | ||
CAG length of mutated allelea |
| 43.3 | (2.4) |
| 42.2 | (3.3) |
|
|
|
|
| 0.273 | ||
Estimated years to onseta,h |
| 6.5 | (4.1) |
| 22.3 | (10.7) |
|
|
|
|
| <0.001*** | ||