Parameter

At start

After combination diuretics

(After high-dose Lasix)

3 days after addition of Aldactone

3 days after further addition of Thiazides/Metalazone

Serum creatinine (umol/L)

210 (40)

230 (30)

240 (30)

estimated GFR (ml/min/1.73m²)

25 (10)

23 (8)

22 (8)

FE Na%

1.2 (0.2)

1.6 (0.2)

1.9 (0.1)

Body weight (Kg)

98 (11)

95 (12)

90 (11)

sPAP (mm Hg)

75 (5)

59 (7)

27 (4)