Risk factors | HIV positive infant | HIV negative infant | odds ratio 95% CI | P |
Maternal age |
|
|
|
|
Maternal age < 35 years | 9 | 247 | 1 |
|
Maternal age > 35 years | 4 | 28 | 0.25 [0.07 - 0.88] | 0.043 |
Parity |
|
|
|
|
Primiparous | 8 | 22 | 1 |
|
Multiparous | 5 | 253 | 18.4 [5.55 - 61.05] | <0.001 |
Education level |
|
|
|
|
Low level of education | 10 | 159 | 1 |
|
Secondary and University level | 3 | 116 | 2.43 [0.65 - 9.03] | 0.14 |
Period of discovery of HIV status |
| |||
Antenatal Discovery | 4 | 259 | 1 |
|
Discovery during labor or postnatal | 9 | 16 | 0.03 [0.01 - 0.10] | <0.001 |
Maternal WHO HIV clinical stage |
| |||
Clinical stage 1 | 2 | 265 | 1 |
|
Clinical stage 2 and 3 | 11 | 10 | 31.45 [16.04 - 64.73] | <0.001 |
Maternal CD4 count (n = 162) |
| |||
CD4 < 200/mm3 | 9 | 20 | 1 |
|
CD4 > 200/mm3 | 4 | 129 | 14.51[4.08 - 51.59] | <0.001 |
VL of the mother (n = 95) |
|
|
|
|
VL > 1000 copies/mm3 | 10 | 22 | 1 |
|
VL < 1000 copies/mm3 | 3 | 60 | 9.09 [2.28 - 36.12] | <0.001 |
Labor time |
|
|
|
|
Prolonged labor (>12 h) | 10 | 58 | 1 |
|
normal hours of Labor | 3 | 217 | 12.47 [3.32 - 46.79] | <0.001 |
Premature rupture of membranes |
| |||
Presence of a PrM | 9 | 20 | 1 |
|
Absence of a PRM | 4 | 255 | 24.94 [7.12 - 87.30] | <0.001 |
Birth weight |
|
|
|
|
Weight less than 2500 g | 9 | 89 | 1 |
|
Weight of 2500 g and more | 4 | 186 | 4.70 [1.40 - 15.68] | 0.014 |
Newborn breastfeeding method |
| |||
Strict Breastfeeding | 3 | 266 | 1 |
|
Mixed or artificial breastfeeding | 10 | 9 | 98.51 [23.08 - 420.49] | <0.001 |