Performance of cognitive tests on day A and day B before intake (0h)

Performance of d2 Test (d2)

Placebo

Zem25

Zem50

Day A (acute)

Mean

10.12

10.60

10.41

SD

3.07

2.98

3.05

Day B (repetitive)

Mean

11.50

11.85

11.91

SD

3.45

2.81

2.31

p < 0.10

Performance of Memory Test (ME)

Placebo

Zem25

Zem50

Day A (acute)

Mean

5.90

6.82

6.22

SD

2.59

3.25

2.82

Day B (repetitive)

Mean

6.14

7.25

6.48

SD

2.90

2.51

2.40

Performance of Arithmetic Calculation Test (CPT)

Placebo

Zem25

Zem50

Day A (acute)

Mean

2.17

3.33

2.97

SD

1.75

2.86

2.93

Day B (repetitive)

Mean

2.63

3.40

2.53

SD

2.02

2.94

1.76

Performance of Reaction Time Test (RT)

Placebo

Zem25

Zem50

Day A (acute)

Mean

431.15

432.52

422.36

SD

32.32

29.77

47.44

Day B (repetitive)

Mean

419.57

417.30

421.90

SD

40.21

39.99

35.70

Performance of Number Identifying Test (NIT)

Placebo

Zem25

Zem50

Day A (acute)

Mean

29.10

28.63

28.23

SD

1.91

2.97

4.18

Day B (repetitive)

Mean

28.32

30.64

28.89

SD

6.09

0.89

2.79

p < 0.01

Performance of Number Connection Test (NCT)

Placebo

Zem25

Zem50

Day A (acute)

Mean

115.88

139.90

110.66

SD

43.33

27.97

42.12

Day B (repetitive)

Mean

137.60

150.27

127.82

SD

36.53

29.21

31.20

p < 0.10