Allocation

proportion

Subject-level

costs

Study designs

CO1

CO2

CO3

BM

1.02

1.01

1.04

1.58

1.15

1.09

1.14

1.84

0.89

0.92

0.94

1.33

0.99

0.99

0.99

1.00

0.97

0.97

0.97

0.99

1.02

1.02

1.02

1.01

0.98

0.98

0.96

1.53

0.82

0.87

0.82

1.26

1.15

1.11

1.08

1.81