Parameter

Low MACC-1 Expression

n = 17

High MACC-1 Expression

n = 29

P value

Age

45.6 ± 11.82

58.5 ± 14.84

<0.05

Gender

Male(n = 31)

35.5% (11/31)

64.5% (20/31)

NS

Female (n = 15)

40% (6/15)

60% (9/15)

Location

Cardia (n = 9)

33.3% (3/9)

66.7% (6/9)

NS

Body (n = 17)

35.3% (6/17)

64.7% (11/17)

Antrum (n = 20)

40% (8/20)

60% (12/20)

Tumor size

<5 cm (n = 19)

63.2% (12/19)

36.8% (7/19)

<0.05

≥5 cm (n = 27)

18.5% (5/27)

81.5% (22/27)

Histological classification

Papillary adenocarcinoma (n = 7)

28.6% (2/7)

71.4% (5/7)

NS

Tubular adenocarcinoma (n = 22)

36.4% (8/22)

63.6% (14/22)

Mucinous adenocarcinoma (n = 8)

37.5% (3/8)

62.5% (5/8)

Signet-ring cell carcinoma (n = 9)

44.4% (4/9)

55.6% (5/9)

Invasion depth

T 1,2 (n = 18)

66.7% (12/18)

33.3% (6/18)

<0.05

T 3,4 (n = 28)

17.9% (5/28)

82.1% (23/28)

LN involvement

NO (n = 14)

71.4% (10/14)

28.6% (4/14)

<0.05

YES (n = 32)

21.9% (7/32)

78.1% (25/32)

Distant metastasis

M0 (n = 32)

43.7% (16/32)

50% (16/32)

<0.05

M1 (n = 14)

7.1% (1/14)

92.9% (13/14)

TNM stages

I, II (n = 16)

68.7% (11/16)

31.3% (5/16)

<0.05

III, IV (n = 30)

20% (6/30)

80% (24/30)