Cytogenetic Markers

Pediatric T-ALL

Adult T-ALL

Age

Age

1 - 10 years

11 - 15 years

<40 years

>40 years

Pos

Neg

Pos

Neg

p-value

Pos

Neg

Pos

Neg

p-value

del(9p)

109 (61%)

111 (49%)

70 (39%)

115 (51%)

0.018

147 (95%)

255 (79%)

8 (5%)

66 (21%)

0.0005

MLL translocations

9 (47%)

205 (56%)

10 (53%)

160 (44%)

0.452

5 (83%)

328 (84%)

1 (17%)

62 (16%)

0.959

TCRα, TCRβ, TLX1, TLX3

72 (56%)

130 (52%)

56 (44%)

119 (48%)

0.467

102 (90%)

285 (83%)

12 (10%)

58 (17%)

0.101