Cytogenetic Markers

Adult T-ALL

Pediatric T-ALL

Frequency

Frequency

Present Study

Western population

Present Study

Western population

Hypodiploidy

Low Hypodiploidy

High Hypodiploidy

20%

5%

15%

-

18%

2%

16%

-

Hyperdiploid

Low Hyperdiploidy

High Hyperdiploidy

14%

12%

2%

-

11%

10%

1%

-

Tri-tetraploidy

5%

-

5%

-

del(9p)

32%

40% - 50%

44%

50% - 60%

MLL translocations

1.3%

4%

5%

-

TCRα, TCRβ

18%

20% - 30%

21%

20% - 30%

TLX1

4%

15% - 20%

2.4%

5% - 10%

TLX3

8%

10% - 20%

11%

20%