Cytogenetic Markers | Pediatric BCP-ALL | p-value | Adult BCP-ALL | p-value | ||||||
Age | Age | |||||||||
1 - 10 years | 11 - 15 years | <40 years | >40 years | |||||||
Pos | Neg | Pos | Neg | Pos | Neg | Pos | Neg | |||
+4, +10, +17 | 368 (90%) | 428 (74%) | 39 (10%) | 151 (26%) | 0.0005 | 64 (77%) | 273 (78%) | 19 (23%) | 77 (22%) | 0.826 |
t(9;22) | 90 (58%) | 1803 (80%) | 65 (42%) | 448 (20%) | 0.0005 | 235 (66%) | 755 (80%) | 122 (34%) | 186 (20%) | 0.0005 |
t(12;21) | 271 (93%) | 1613 (77%) | 20 (7%) | 488 (23%) | 0.0005 | - | - | - | - | - |
MLL translocations | 66 (89%) | 1825 (78%) | 8 (11%) | 505 (22%) | 0.025 | 22 (71%) | 967 (77%) | 9 (29%) | 297 (23%) | 0.474 |
t(1;19) | 127 (75%) | 1737 (79%) | 42 (25%) | 456 (21%) | 0.213 | 51 (91%) | 922 (76%) | 5 (9%) | 290 (24%) | 0.009 |