| Method 1 | Method 2 | Method 3a | ||||||
Variables | AUC OOB* | Variables | AUC OOB* | Variables | AUC OOB** (LR part) | AUC OOB** (LDA part) | AUC OOB*** (all) | ||
1 | NT-proBNP | 0.7246 | NT-proBNP | 0.7246 | NT-proBNP | 0.7246 | 0.7246 | 0.7246 | |
2 | NYHA ≥ III | 0.7482 | NYHA ≥ III | 0.7482 | NYHA ≥ III | 0.7482 | 0.7523 | 0.7523 | |
3 | Periph. edema ≥ “above” | 0.7547 | Heart rate | 0.7529 | NYHA ≥ II | 0.7550 | 0.7579 | 0.7579 | |
4 | Glycemia | 0.7620 | Systolic BP | 0.7591 | Glycemia | 0.7621 | 0.7642 | 0.7642 | |
5 | Systolic BP | 0.7671 | NYHA ≥ II | 0.7647 | Periph. edema ≥ “above” | 0.7687 | 0.7688 | 0.7694 | |
6 | Beta-blockers | 0.7730 | Beta-blockers | 0.7696 | Beta-blockers | 0.7731 | 0.7714 | 0.7736 | |
7 | NYHA ≥ II | 0.7787 | Glycemia | 0.7764 | Systolic BP | 0.7791 | 0.7761 | 0.7792 | |
8 | Cholesterol HDL | 0.7829 | Periph. edema ≥ “above” | 0.7810 | Cholesterol HDL | 0.7835 | 0.7796 | 0.7835 | |
9 | Mean BP | 0.7827 | Cholesterol HDL | 0.7852 | Paroxystic AF | 0.7864 | 0.7831 | 0.7867 | |
10 | Diastolic BP | 0.7840 | Uricemia | 0.7885 | Uricemia | 0.7902 | 0.7866 | 0.7904 | |
11 | Heart rate | 0.7861 | Bilirubin | 0.7912 | Bilirubin | 0.7925 | 0.7876 | 0.7926 | |
12 | Uricemia | 0.7897 | Diuretics | 0.7913 | Implantable defibrillator | 0.7948 | 0.7908 | 0.7950 | |
13 | Third heart sound | 0.7922 | Previous AMI | 0.7932 | Neoplasia | 0.7966 | 0.7924 | 0.7968 | |
14 | Bilirubin | 0.7950 | Paroxystic AF | 0.7953 | Third heart sound | 0.7984 | 0.7947 | 0.7985 | |
15 | Previous AMI | 0.7967 | Third heart sound | 0.7982 | Heart rate | 0.8001 | 0.7963 | 0.8002 | |
16 | Paroxystic AF | 0.7988 | LVEF | 0.7990 | Previous AMI | 0.8020 | 0.7977 | 0.8020 | |
17 | Implantable defibrillator | 0.8010 | Triglycerides | 0.8006 | Triglycerides | 0.8038 | 0.7993 | 0.8038 | |
18 | Neoplasia | 0.8027 | Neoplasia | 0.8028 | LVEF | 0.8052 | 0.8010 | 0.8052 | |
19 | LVEF | 0.8045 | Ascitis | 0.8038 | Hypertension | 0.8067 | 0.8021 | 0.8067 | |
20 | Triglycerides | 0.8064 | Implantable defibrillator | 0.8060 | Mitral insufficiency | 0.8080 | 0.8040 | 0.8080 | |
21 | Diuretics | 0.8070 | Hemoglobin | 0.8058 | Smoker or ex-smoker | 0.8091 | 0.8053 | 0.8091 | |
22 | Ascitis | 0.8085 | ePVS | 0.8061 | Ascitis | 0.8104 | 0.8060 | 0.8104 | |
23 | Mid-apical pulmonary rales | 0.8091 | Hematocrit | 0.8070 | Periph. edema ≥ “ankles” | 0.8116 | 0.8069 | 0.8116 | |
24 | Smoker or ex-smoker | 0.8099 | Smoker or ex-smoker | 0.8080 | NYHA ≥ IV | 0.8119 | 0.8071 | 0.8119 | |
25 | Mitral insufficiency | 0.8108 | Mitral insufficiency | 0.8086 | BMI | 0.8130 | 0.8084 | 0.8130 | |
26 | Hypertension | 0.8121 | BMI | 0.8103 | Mid-apical pulmonary rales | 0.8137 | 0.8084 | 0.8137 | |
27 | BMI | 0.8131 | Hypertension | 0.8119 |
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28 | Periph. edema ≥ “ankles” | 0.8144 | Previous hosp. for worsening HF | 0.8119 |
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29 | Periph. edema ≥ “knee” | 0.8151 | Mid-apical pulmonary rales | 0.8127 |
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30 | CABG | 0.8157 | Diabetes | 0.8127 |
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31 | Calcium antagonists | 0.8161 | CABG | 0.8133 |
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32 | Previous hosp. for worsening HF | 0.8166 | Periph. edema ≥ “knee” | 0.8136 |
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33 | Bundle branch block | 0.8170 | Diastolic BP | 0.8137 |
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34 | NYHA ≥ IV | 0.8176 | NYHA ≥ IV | 0.8145 |
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35 | Serum sodium | 0.8178 | Bundle branch block | 0.8147 |
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36 | Diabetes | 0.8180 | Calcium antagonists | 0.8153 |
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37 | COPD | 0.8181 | Total cholesterol | 0.8149 |
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38 | Previous stroke | 0.8184 | Mean BP | 0.8151 |
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39 | Years of school education | 0.8187 | COPD | 0.8150 |
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40 | Age | 0.8186 | Periph. edema ≥ “ankles” | 0.8163 |
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41 | Weight | 0.8186 | Atrial fibrillation | 0.8166 |
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42 | Serum creatinine | 0.8185 | Cause of HF = “not known” | 0.8165 |
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43 | eGFR | 0.8186 | Previous stroke | 0.8167 |
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44 | Total cholesterol | 0.8184 | Aortic stenosis | 0.8167 |
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45 | Aortic stenosis | 0.8185 | Age | 0.8164 |
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46 | Cause of HF = “not known” | 0.8186 | Angina pectoris | 0.8164 |
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47 | Atrial fibrillation | 0.8187 | Years of school education | 0.8166 |
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48 | Pulmonary rales | 0.8186 | Waiting for cardiac transplantation | 0.8168 |
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49 | Basal pulmonary rales | 0.8188 | Serum sodium | 0.8170 |
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50 | Transient ischemic attack | 0.8187 | Definitive pace maker | 0.8171 |
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51 |
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| Basal pulmonary rales | 0.8168 |
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52 |
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| Weight | 0.8169 |
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53 |
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| eGFR | 0.8169 |
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54 |
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| Transient ischemic attack | 0.8170 |
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55 |
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| Hepatomegaly | 0.8165 |
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56 |
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| Pulmonary rales | 0.8168 |
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57 |
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| ECG evaluation | 0.8167 |
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58 |
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| ACE-inhibitors | 0.8172 |
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59 |
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| Serum creatinine | 0.8168 |
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60 |
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| Serum potassium | 0.8170 |
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61 |
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| CVP > 6 cm H20 | 0.8170 |
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62 |
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| Cause of HF = “cardiomyopathy” | 0.8167 |
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