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| Melancholic depression (Traditional-type depression: TTD) | “Modern-type” depression (MTD) |
| Ages | Middle age (born before 1970) | Young age (born after 1970) |
| Characters | Attachment to rules | Attachment to self separately from social roles |
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| Love of order, models | Distress over rules/order |
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| Sympathetic | Negative feelings toward order or model |
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| Obsessive | Vague sense of omnipotence |
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| Honest | Not hard worker to begin with |
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| Hard worker |
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| Symptoms | Agitation or retardation | Fatigue and not feeling good enough |
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| Exhaustion and guilt | Avoidance and blame of others |
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| Well-prepared suicide | Impulsive suicidal action |
| Therapeutic relationship | Resist diagnosis of depression | Cooperate with diagnosis of depression |
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| When recovered, learn from experience of depression | Tend to self-check depressive symptoms |
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| Have difficulty departing from diagnosis (prefer to stay in “depression”) |
| Drug response | Usually good | Partial response |
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| Complete remission |
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| Cognition | Obtaining a new sense of role (e.g., self as a manager to self as a manager who has experienced depression) | Have difficulty departing from “I suffer from depression” |
| Prognosis | Good response to rest and antidepressants | Become chronically ill only with rest and antidepressants |
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| Ambivalent about change of environment | Change of environment rapidly improves symptoms |