Source of

Variation

DF

SS

MS

EMS

Patient

a − 1

S S A = i = 1 a n ( m i M ) 2

M S A = S S A a 1

n 2 + σ 2

Within

Patient

a (n − 1)

S S E = i a j = 1 n n ( x i j m i ) 2

M S E = S S E a ( n 1 )

σ 2

Total

an − 1

S S T = i a j = 1 n n ( x i j M ) 2

M S T = S S T a n 1